Lisa Hoffman

L. Hoffman

Credentials:

PhD

Affiliations

Imaging Scientist, Lawson Health Research Institute Assistant Professor, Departments of Medical Biophysics, and Anatomy & Cell Biology, Western University Molecular Imaging Collaborative Graduate Program MSK Research Group, Western BIRC, Western

Biography

Dr. Hoffman obtained her Ph.D. from the University of Saskatchewan in 2000. She went on to complete several postdoctoral positions that culminated in a unique skill set in stem cell biology, classic cell/molecular biology, and non-invasive multi-modality imaging. Imaging modalities include positron emission tomography [PET], dynamic contrast-enhanced computed tomography [DCE-CT], high frequency 3D ultrasound [HFU]/echocardiography, and optical/bioluminescense imaging . She is currently one of few Canadian researchers poised to take advantage of the recent opening of the PETtracer Cyclotron and PET-radiochemistry facility in London. Dr. Hoffman was appointed as a Lawson Imaging Scientist in the Fall of 2009, and as Asistant Professor in the Departments of Medical Biophysics , Western University (Fall 2009) and Anatomy & Cell Biology, Western University (Spring 2010). Capitalizing on the breadth of her multidisciplinary experience, Dr. Hoffman's current research interests lie in Molecular Imaging and Cell Therapeutics for the treatment of both the skeletal and cardiac manifestations of Duchenne muscular dystrophy (DMD). Specifically, her group aims to develop objective and quantitative non-invasive imaging technologies to track stem/progenitor cell fate following transplantation into mouse models of DMD. Her growing expertise in this area of research has been recognized by her being awarded a Stem Cell Network (SCN) Transitional Research Grant in 2008. She has additionally held internal operating funds (IRF) with Lawson (2009-2010), and a CIHR Priority Announcement from the Institute of Musculoskeletal Health and Arthritis in 2010. She currently holds another Lawson IRF (2011-2012), a NSERC Discovery Grant (2011-2016), and a HSFO Grant-In-Aid (2012-2014). EDUCATION May 2000: Ph.D. (Anatomy and Cell Biology), University of Saskatchewan, SK, Canada Thesis title: Effects of Ethanol on Cartilage Differentiation In Vitro. May 1993: B.Sc. Advanced (Anatomy), University of Saskatchewan, SK, Canada RESEARCH EXPERIENCE 2009/10-Present University of Western Ontario, London, ON, Canada Assistant Professor, Depts. Medical Biophysics (Home), Anatomy & Cell Biology (Cross-Appointment, Spring 2010) Research areas: 1) functional and molecular imaging, 2) stem cell therapy for DMD 2009-Present Lawson Health Research Institute, London, ON, Canada Scientist 2007 – 2009 Lawson Health Research Institute, London, ON, Canada Research Associate 2005 – 2007 Lawson Health Research Institute, London, ON, Canada Postdoctoral Fellow 2004-2005 Robarts Research Institute, London, ON, Canada Postdoctoral Fellow Research areas: 1) Cell signaling, and 2) X-chromosome inactivation/imprinting in hESCs 2002-2004 CIHR Group in Skeletal Development and Remodeling University of Western Ontario, London, ON, Canada Postdoctoral Fellow Research area: Mechanisms regulating chondrogenic differentiation 2000-2002 Ottawa Health Research Institute, Ottawa, ON, Canada Postdoctoral Fellow Research area: Regulation of patterning genes in fin/limb development 1993 Department of Anatomy and Cell Biology May-Aug University of Saskatchewan, Saskatoon, SK, Canada Research Assistant Research area: Mechanisms regulating chondrogenic differentiation

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