Brain Injury

Two significant problems facing the Canadian Forces (CF) are Mild Traumatic Brain Injury (MTBI) and Post-Traumatic Stress Disorder (PTSD). For example, structural MRI or CT scans are usually normal in concussive injury and have limited sensitivity. Thus, diagnoses often rely on subjective assessments (psychiatric and neuropsychological testing). We hypothesize that functional imaging will provide insight into the pathophysiological and functional sequelae of these disorders.

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Researchers
R.Z. Stodilka
Nuclear medicine physics
A. Legros
Bioelectromagnetics
A.W. Thomas
Director, Bioelectromagnetics
W.F. Pavlosky
Radiology
J. Théberge
Magnetic Resonance Physics
R.T. Thompson
Director, MR Spectroscopy
K. St. Lawrence
Magnetic Resonance Physics
F.S. Prato
Imaging Program Leader

Technologies
3T PET/MR
Human Threshold Testing Facility

Collaborators


Future Directions

Our portable neurophysiologic monitoring technology is presently undergoing military field trials. We are also developing imaging technology as a detailed follow-up to the portable neurophysiologic test. Clinical populations are being recruited through trauma units and psychiatric practices in Southwestern Ontario. Lawson’s MRI/EEG capabilities allow us to conduct a multi-parametric functional / anatomical assessment and will allow us to investigate changes in brain blood flow, brain functional responses, metabolite concentrations and electrical activity.

Key Accomplishments

We have developed portable neurophysiologic monitoring technology to diagnose MTBI. Our technology relies upon alterations in postural tremor, which we measure non-invasively using portable self-powered instrumentation. Testing takes 60 seconds.

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